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Canine lymphoma prednisone
Canine lymphomas are a diverse group of cancers, and are among the most common cancers diagnosed in canine lymphoma prednisone dogs. They collectively represent approximately 7-14 of all cancers diagnosed in dogs. There are over 30 described types of canine lymphoma, and these cancers vary tremendously in their behavior. Some progress rapidly and are acutely life-threatening without treatment, while others progress very slowly and are managed as chronic, indolent diseases. Lymphomas may affect any organ in the body, but most commonly originate in lymph nodes, before spreading to other organs such as the spleen, liver, and bone marrow. Canine lymphomas are similar in many ways to the non-Hodgkin's lymphomas (NHL) which occur in humans. Canine lymphomas and NHL are nearly indistinguishable when examined microscopically, and both tumor types exhibit similar responses to chemotherapy. In 2010, NHL was diagnosed in approximately 65,000 people in the United States, and claimed approximately 20,000 lives, making it the 7th-most common cancer overall, and the 6th-most common cause of cancer-related death. It is one of the few human cancers for which the frequency of newly diagnosed cases is still on the rise. It is our hope that research in canine lymphomas conducted by the Purdue Comparative Oncology Program will discover new ways of treating NHL in both dogs and humans. Our goal is to improve the outlook for dogs and humans affected with this all-too-common cancer. Frequently Asked Questions by Pet Owners. The canine lymphoma prednisone term lymphoma describes a diverse group of cancers in dogs that are derived from white blood cells called lymphocytes. Lymphocytes normally function as part of the immune system to protect the body from infection. Although lymphoma can affect virtually any organ in the body, it most commonly arises in organs that function as part of the immune system such as the lymph nodes, spleen, and bone marrow. By far the most common type of lymphoma in the dog is multicentric lymphoma, in which the cancer first becomes apparent in lymph nodes. The photo to the right shows a dog with multicentric lymphoma. Note the swollen mandibular lymph node (white arrow) under the jaw. Other common lymphomas in dogs include cutaneous lymphoma ( lymphoma of the skin alimentary or gastrointestinal lymphoma ( lymphoma of the stomach and/or intestines) and mediastinal lymphoma ( lymphoma involving organs within the chest, such as lymph nodes or the thymus gland). What causes lymphoma in dogs? Unfortunately, the cause of lymphoma in dogs is not known. Although several possible causes such as viruses, bacteria, chemical exposure, and physical factors such as strong magnetic fields have canine lymphoma prednisone been investigated, the cause of this cancer remains obscure. Suppression of the immune system is a known risk factor for the development of lymphoma in humans. Evidence for this includes increased rates of lymphoma in humans infected with the HIV virus or are on immune-suppressing drugs following organ transplantation surgery. However, the link between immune suppression and lymphoma in dogs is not clearly established. What are the most common symptoms of canine lymphoma? The most common initial symptom of multicentric lymphoma in dogs is firm, enlarged, non-painful lymph nodes. A lymph node affected by lymphoma will feel like a hard, rubbery lump under your dogs skin. The most easily located lymph nodes on a dogs body are the mandibular lymph nodes (under the jaw) and the popliteal lymph nodes (behind the knee). Other common symptoms include loss of appetite, lethargy, weight loss, swelling of the face or legs ( edema and occasionally increased thirst and urination. . The photo on the left canine lymphoma prednisone shows a dog with edema of the left rear leg. This is caused when a swollen lymph node blocks the normal drainage of fluid from the leg. Cutaneous lymphoma tends to appear first as dry, flaky, red, and itchy patches of skin anywhere on the body. As the disease progresses, the skin becomes moist, ulcerated, very red, and thickened. Masses in the skin can also occur with cutaneous lymphoma. . Cutaneous lymphoma may progress slowly and often has been treated for several months as an infection or allergy before a diagnosis of lymphoma is made. . Cutaneous lymphoma may also appear in the mouth, often affecting the gums, lips, and the roof of the mouth. . Cutaneous lymphoma in the mouth is often mistaken for periodontal disease or gingivitis in its early stages. The photo on the left shows cutaneous lymphoma in the mouth of a dog. . Note the very red gums and the ulceration on the roof of the mouth. Dogs with gastrointestinal lymphoma usually have symptoms such as vomiting, watery diarrhea, and weight loss. The diarrhea is often very dark in color and foulsmelling. Dogs with mediastinal lymphoma typically have difficulty breathing. . This may be due to the presence of a large mass within the chest or due to the accumulation of fluid within the chest ( pleural effusion ). Affected dogs may also show swelling of the face or front legs as well as increased thirst and urination.